abstract：INTRODUCTION:There is increasing interest in measuring mucosal inflammation in Crohn disease (CD), but there are minimal data correlating the Pediatric Crohn's Disease Activity Index (PCDAI) versions (PCDAI, weighted Pediatric Crohn's Disease Activity Index [wPCDAI], abbreviated Pediatric Crohn's Disease Activity Index...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Turner D,Levine A,Walters TD,Focht G,Otley A,López VN,Koletzko S,Baldassano R,Mack D,Hyams J,Griffiths AM

更新日期：2017-02-01 00:00:00

abstract：:Since the first description of celiac disease (CeD) by Samuel Gee in 1888 and the later "miraculous discovery" that bread was responsible for this condition following World War II in Europe, there has been an exponential growth of knowledge regarding CeD. Just when we thought that we knew everything there was to know ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jericho H,Assiri A,Guandalini S

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:Diarrheal diseases are a leading cause of morbidity and mortality worldwide, but the etiology of diarrhea and its relation to nutritional outcomes in resource-limited settings is poorly defined. We sought to determine the etiology of community-acquired diarrhea in Tanzanian infants and to assess the associati...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gosselin KB,Aboud S,McDonald CM,Moyo S,Khavari N,Manji K,Kisenge R,Fawzi W,Kellogg M,Tran HQ,Kibiki G,Gratz J,Liu J,Gewirtz A,Houpt E,Duggan C

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to understand the association between parents' perceptions of the decision process and the decision outcomes in decisions about the use of biologics in pediatric chronic conditions. METHODS:We mailed surveys to parents of children with inflammatory bowel disease or juvenile idiopath...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lipstein EA,Lovell DJ,Denson LA,Kim SC,Spencer C,Ittenbach RF,Britto MT

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the multidimensional gastrointestinal symptoms predictors of generic health-related quality of life (HRQOL) in pediatric patients with inflammatory bowel disease from the perspectives of pediatric patients and parents. METHODS:The Pediatric Quality of Life Inventory G...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Varni JW,Shulman RJ,Self MM,Saeed SA,Patel AS,Nurko S,Neigut DA,Saps M,Franciosi JP,Denham JM,Zacur GM,Dark CV,Bendo CB,Pohl JF,Pediatric Quality of Life Inventory Gastrointestinal Symptoms Module Testing Study Consortium.

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The respective role of disease activity and steroid therapy in growth impairment in paediatric-onset Crohn disease (CD) is still debated. Our aim was to investigate whether the growth pattern of children with CD was correlated with the inflammatory status during the disease course, regardless the cumulative ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ley D,Duhamel A,Behal H,Vasseur F,Sarter H,Michaud L,Gower-Rousseau C,Turck D

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The etiological factors of chronic pancreatitis (CP) in children differ from those in adults. To date, no study has assessed the clinical course of CP in young children. The aim of our study was to evaluate the etiology and the clinical presentation of the disease in children with disease onset before 5 year...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wejnarska K,Kolodziejczyk E,Wertheim-Tysarowska K,Dadalski M,Sobczynska-Tomaszewska A,Kierkus J,Bal J,Rygiel AM,Oracz G

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Brain-gut axis signaling modifies gastrointestinal symptomatology. Altered neural processing of intestinal pain signals involves interoceptive brain regions in adults with functional and inflammatory gastrointestinal disorders. Although these disorders frequently present in childhood, there are no published ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Huang JS,Terrones L,Simmons AN,Kaye W,Strigo I

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Iron deficiency anemia (IDA) is common in children with inflammatory bowel disease (IBD) affecting their cognitive development and school performance. Oral iron supplementation has serious limitations including poor adherence and iron malabsorption related to chronic inflammation. Our objective was to evalua...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Danko I,Weidkamp M

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:The prevalence of ulcerative colitis (UC) differs by country, which is likely due to differences in genetic factors among ethnicities. Moreover, the prevalence of pediatric UC with a family history (FH) is 4.1% in Japanese patients; its clinical course begins at an early age and is more severe. Recently, a g...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fujii T,Sato M,Hosoi K,Ohbayashi N,Ikuse T,Jimbo K,Aoyagi Y,Kudo T,Ohtsuka Y,Shimizu T

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Eosinophilic esophagitis (EoE) can present as food selectivity or feeding disorders in children. Children with autism spectrum disorders (ASDs) commonly demonstrate behavioral food selectivity in type and texture, which often leads to the diagnosis of feeding disorder. We sought to evaluate the association o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Heifert TA,Susi A,Hisle-Gorman E,Erdie-Lalena CR,Gorman G,Min SB,Nylund CM

更新日期：2016-10-01 00:00:00

abstract：:Anti-tumor necrosis factor-alpha (TNF-α) blockade is so far the most effective therapy for extensive pediatric Crohn disease (CD), but loss of response is frequently encountered. We describe here the use of golimumab (Simponi) in 6 pediatric CD patients with antibody formation/loss of response to infliximab and adalim...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Merras-Salmio L,Kolho KL

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Gastrointestinal (GI) symptoms of nausea, vomiting, and abdominal pain are common in patients with orthostatic intolerance (OI), including neurally mediated hypotension (NMH) and postural orthostatic tachycardia syndrome (POTS). Autonomic dysregulation is considered the underlying pathophysiology behind the ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Moak JP,Fabian RR,Clarke LC,Hanumanthaiah S,Desbiens J,Darbari A

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine whether embedding into the radiology report a patient-specific plan in the event of gastrojejunostomy (GJ) tube dysfunction reduces the need for after-hours utilization of pediatric interventional radiology resources for the replacement of GJ tubes. MATERIALS AND METHOD...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sharafinski ME Jr,Sehnert E,Moe D,Zhang L,Simpson P,Vo NJ

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Gastroesophageal reflux is common but remains a controversial disease to diagnose and treat and little is known about the role of reflux testing in predicting clinical outcomes, particularly in children at risk for extraesophageal reflux complications. The aim of this study was to determine if rates of hospi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Duncan DR,Amirault J,Johnston N,Mitchell P,Larson K,Rosen RL

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:X-linked inhibitor of apoptosis (xIAP) deficiency is a primary immune deficiency disorder associated with hemophagocytic lymphohistiocytosis. About 17% of xIAP-deficient patients present with very early onset severe colitis with high mortality. We hypothesized that xIAP deficiency leads to defective generatio...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gurram B,Hammelev E,Syverson G,Haribhai D,Yan K,Simpson P,Salzman N,Verbsky JW

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Lactase nonpersistence (LNP) in humans is a genetically determined trait. This age-dependent decrease of lactase expression is most frequently caused by single nucleotide polymorphisms in the regulatory region of the lactase (LCT) gene. The homozygous LCT-13,910C/C genotype (rs 4988235) predominates in Cauca...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alliende F,Vial C,Espinoza K,Schnettle D,Romero V,Miquel I,Arancibia ME,Rios G,Rodriguez L,Quesada S,Lucero Y,Repetto GM

更新日期：2016-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Clinical evidence of the use of probiotics in pediatric NAFLD, framed within gut microbiota response, is herein discussed. RECENT FINDINGS:The assistance of a new microbiological approach in probiotics' design is playing a central role in NAFLD clinical management. Experimental studies demonstrated t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Putignani L,Alisi A,Nobili V

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Biliary dyskinesia is a common diagnosis that frequently results in cholecystectomy. In adults, most clinicians use a cut off value for the gallbladder ejection fraction (GBEF) of <35% to define the disease. This disorder is not well characterized in children. Our aim was to determine the relation between GB...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jones PM,Rosenman MB,Pfefferkorn MD,Rescorla FJ,Bennett WE Jr

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Electrolyte-free polyethylene glycol powder (PEG-3350) has been widely used for colonoscopy preparation (prep); however, limited safety data on electrolyte changes exists with 1-day prep regimens. The primary aim of this study was to determine the proportion of patients with significant serum chemistry abnor...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sahn B,Chen-Lim ML,Ciavardone D,Farace L,Jannelli F,Nieberle M,Ely E,Zhang X,Kelsen J,Puma A,Mamula P

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To conduct a comprehensive study of postendoscopic adverse events (AEs) in children, categorizing them by the level of intervention required. BACKGROUND:Previous studies of endoscopic AE in children have focused on intraprocedural and short-term outcomes, such as bleeding, perforation, and infection, and may...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kramer RE,Narkewicz MR

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Standardized outcome measures provide a basis for comparing outcomes of different clinical trials. Consequently, they can serve as the foundation for determining which therapeutic interventions are most effective. The aim of the present study is to systematically assess how definitions and outcome measures ar...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kuizenga-Wessel S,Heckert SL,Tros W,van Etten-Jamaludin FS,Benninga MA,Tabbers MM

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVES:Cow's milk allergy (CMA) is the most common food allergy in children with many clinical manifestations, leading to misdiagnoses such as gastro-oesophageal reflux, infantile colic, and lactose intolerance with inappropriate prescribing. We aimed to determine the impact of infant feeding guidelines on CMA pres...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wauters L,Brown T,Venter C,Dziubak R,Meyer R,Brogan B,Walsh J,Fox AT,Shah N

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to assess health-related quality of life (HRQOL) using the Coeliac Disease Dutch Questionnaire (CDDUX) in Spanish children with coeliac disease. METHODS:The CDDUX was cross-culturally adapted according to international consensus guidelines. HRQOL was assessed in coeliac members of t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Barrio J,Román E,Cilleruelo M,Márquez M,Mearin ML,Fernández C

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:Impaired growth has been reported in children born with esophageal atresia (EA). Their nutritional fate at adulthood remains uncertain though. Our objectives were to determine the body mass index (BMI) of adult patients with EA followed up from 2009 to 2011 in the EA clinic of a university-affiliated hospita...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Presse N,Taillefer J,Maynard S,Bouin M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Vitamin D is known to have modulatory actions in the immune system. Its influence on the severity of lower tract acute respiratory infections (LT-ARIs) is unclear. OBJECTIVES:The aim of the present study was to evaluate the role of vitamin D on LT-ARI in paediatric patients. METHODS:Children admitted to ho...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cebey-López M,Pardo-Seco J,Gómez-Carballa A,Martinón-Torres N,Rivero-Calle I,Justicia A,Redondo L,Martinón-Sánchez JM,Martínez-Padilla Mdel C,Giménez-Sánchez F,Salas A,Martinón-Torres F,GENDRES Network.

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:Parents of children with autism spectrum disorders (ASDs) often report gastrointestinal (GI) dysfunction in their children. The objectives of the present study were to determine whether infants at high risk for developing ASD (ie, siblings of children diagnosed as having ASD) show greater prevalence of GI pr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Penn AH,Carver LJ,Herbert CA,Lai TS,McIntire MJ,Howard JT,Taylor SF,Schmid-Schönbein GW,Dobkins KR

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Hepatic lesions have been described in Alagille syndrome (ALGS) in isolated case reports, and most of these have been reported to be hepatocellular carcinoma. OBJECTIVES:The aim of the present study was to determine the frequency, imaging, and histopathologic characteristics of hepatic lesions in children w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alhammad A,Kamath BM,Chami R,Ng VL,Chavhan GB

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:A large retrospective multicentre study was conducted in Spain to evaluate the efficiency of the new European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) criteria for the diagnosis of coeliac disease (CD). METHODS:The study protocol was approved by the ethics committee of Hos...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Donat E,Ramos JM,Sánchez-Valverde F,Moreno A,Martinez MJ,Leis R,Peña-Quintana L,Castillejo G,Fernández S,Garcia Z,Ortigosa L,Balmaseda E,Marugán JM,Eizaguirre FJ,Lorenzo H,Barrio J,Ribes-Koninckx C,SEGHNP Working Group

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to quantify absorption coefficients of specific fatty acids in preterm infants as a function of diet, formula or breast milk (BM), and postnatal age; to identify the fatty acid structural characteristics that determine optimal fatty acid absorption. METHODS:Fatty acids from ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Martin CR,Cheesman A,Brown J,Makda M,Kutner AJ,DaSilva D,Zaman M,Freedman SD

更新日期：2016-01-01 00:00:00

abstract：:Partially hydrolyzed formulas (pHFs) are increasingly used worldwide, both in the prevention of atopic disease in at-risk infants and in the therapeutic management of infants with functional gastrointestinal manifestations. Because prevention is always preferable to treatment, we reviewed the literature aiming to find...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vandenplas Y,Alarcon P,Fleischer D,Hernell O,Kolacek S,Laignelet H,Lönnerdal B,Raman R,Rigo J,Salvatore S,Shamir R,Staiano A,Szajewska H,Van Goudoever HJ,von Berg A,Lee WS

更新日期：2016-01-01 00:00:00

abstract：:Long-term follow-up of randomised trials and observational studies provide the best evidence presently available to assess long-term effects of nutrition, and such studies are an important component in determining optimal infant feeding practices. Attrition is, however, an almost inevitable occurrence with increasing ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fewtrell MS,Domellöf M,Hojsak I,Hulst JM,Kennedy K,Koletzko B,Mihatsh W,Stijnen T

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Predicting short-term relapses and long-term prognosis is of utmost importance in paediatric inflammatory bowel disease (IBD). Our aim was to investigate the short-term disease outcome and medication during the first year in a paediatric incident cohort from Hungary. In addition, association laboratory marke...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Müller KE,Lakatos PL,Kovacs JB,Arato A,Varkonyi A,Nemes E,Tarnok A,Toth G,Papp M,Solyom E,Horvath A,Guthy I,Kovacs M,Veres G,Hungarian Pediatric IBD Registry Group.

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:The clinical presentation of colonic juvenile polyps with abdominal discomfort and occult rectal bleedings make them difficult to recognize. The aim of this study was to report the clinical features of colonic juvenile polyps in children referred to colonoscopy and evaluate fecal calprotectin (FCP) as a scre...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Olafsdottir I,Nemeth A,Lörinc E,Toth E,Agardh D

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:The primary aim of this study was to describe and compare the clinical characteristics of 2 groups of children presenting to a feeding clinic: children with autism spectrum disorder (ASD) and children with a nonmedically complex history (NMC). A secondary aim was to compare participants according to the degr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Marshall J,Hill RJ,Ware RS,Ziviani J,Dodrill P

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Infant formulas provide more protein than breast milk. High protein intakes may place infants at risk of later obesity. The present study tested whether a formula with protein content below the regulatory level supports normal growth from age 3 months. METHODS:Randomized double-blind trial enrolled healthy ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ziegler EE,Fields DA,Chernausek SD,Steenhout P,Grathwohl D,Jeter JM,Nelson SE,Haschke F

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the in vitro effect(s) of a bovine-based human breast milk fortifier (HMF) on human intestinal cells. HMF increases the expression of BCL2/adenovirus E1B 19 kDa protein-interacting protein (Bnip3) and cell death; the prostaglandin analogue misoprostol will rescue...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Diehl-Jones W,Archibald A,Gordon JW,Mughal W,Hossain Z,Friel JK

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:Previous studies have suggested that hepatitis B virus (HBV) vaccines may be less immunogenic in individuals with celiac disease (CD). A pre-S vaccine (Sci-B-Vac) has demonstrated superior immunogenicity compared with standard HBV vaccines in several diseases. We compared the short-term immunogenicity of a pr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Heshin-Bekenstein M,Turner D,Shamir R,Bar-Meir M,Dagan R,Zevit N,Silbermintz A

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Human milk provides a complex mixture of animal lipids, whereas the fat supply of most modern infant formula is based on vegetable oils. We studied the effects of breast-feeding and of feeding infant formula either without or with dairy goat lipids on the composition of infant plasma glycerophospholipids. ME...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Uhl O,Hellmuth C,Demmelmair H,Zhou SJ,Makrides M,Prosser C,Lowry D,Gibson RA,Koletzko B

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Portopulmonary hypertension (POPH) is a known complication of cirrhosis in adults, but there is little information on its incidence and outcome in children with liver disease. We report 14 patients with POPH and present a synthesis of the medical literature. METHODS:Diagnosis of POPH in the 14 patients was b...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ecochard-Dugelay E,Lambert V,Schleich JM,Duché M,Jacquemin E,Bernard O

更新日期：2015-09-01 00:00:00